I find this approach, described at IEEE Spectrum for modeling the spread of SARS-CoV-2, very appealing:
Current models that track epidemics make predictions about how a disease advances among individuals but don’t take into consideration things that change as it is passed along, such as how a virus mutated or what is being done to control its spread, Poor says. A common model being used for the coronavirus, known as SIR (susceptible, infected, and recovered), is a very basic one for viral spread. He says it doesn’t take into account factors such as underlying health conditions of patients or that some people spread more of COVID-19 droplets than others.
“Previous models for epidemics assumed a pathogen or a piece of information is transferred across network nodes without going through any modifications or evolutionary adaptions,†Poor and his colleagues wrote in that 2019 research article. “[But] in real-life spreading processes, pathogens often evolve in response to changing environments and medical interventions, and the information is often modified by individuals before being forwarded.â€
Once the pandemic hit, Poor realized his model could be applied to COVID-19.
“Contact tracing and social distancing are known by epidemiologists to work so we’re not going to try to prove they do work,†Poor says. “What we’re going to bring to the table is a more refined understanding of when to apply these and other measures and what to expect of them.â€
When people are physically connected, they form what’s called a multi-layered network, Poor says. The network could include family, coworkers, classmates, or social media friends. They, plus their acquaintances, form various degrees of connections, which the researchers call layers.
The researchers will first model these networks using data about the pandemic from a comprehensive data source, known as a data lake, maintained by C3.ai. The database includes the current number of COVID-19 cases, deaths, hospitalizations, and recoveries for countries, including by city, state, province, or county.
“It’s quite extensive, and includes details about COVID-19 victims and spread from a variety of sources globally,†Poor says.
The model can incorporate properties of the spread of the novel coronavirus that have been learned by public health and medical personnel over the past few months, Poor says. That includes the existence of “super spreaders,†asymptomatic spreaders, and delays between when a person becomes contagious and begins showing symptoms. Differences in responses to the virus between populations can also be incorporated into the model, he says, as well as some of the evidence for mutations that has emerged.
I hope they avoid the data from China since I question its veracity. I will look forward to the results of using this approach and don’t wish to prejudge them.
The selection pressure on novel diseases favors variants that have lower mortality and longer infectious periods. With any luck, COVID-19 will mutate into another cold virus, joining the other four, and it will be a nuisance every winter season.
Today’s medical education is specialized in the extreme, probably more so than any other profession, and today’s doctors are pretty ignorant of any biology that does affect their daily practice. Nearly all of them are ignorant about evolutionary theory.
Having spent some time teaching water quality modeling to environmental engineers, I do not take any model too seriously. They are useful to help organize one’s thinking about a particular problem, but it is madness to take the simulations as predictions.
As I’ve mentioned before I constructed my first mathematical model a half century ago and I am well aware of their limitations—you won’t get anything out of them that you didn’t put into them in the first place and they are constrained both by the assumptions and the quality of the data used in constructing them.
However, they may reveal things you hadn’t noticed before and that’s what I’m hoping for.
“super spreaders,â€
I may have it wrong, but I thought it was “super spreader events.”
Such as the incident Friday night last when Lincoln police were called to a residence four blocks north of here involving a fight with 40-50 participants. None were reported wearing masks or social distancing.
News reports say over half of our new positive tests involve those in their twenties. I’d say you can’t stop ’em, not with regulation not with enforcement. None of the party-goers were caught, they were all too fast.
OT, sort of. Link goes to nice paper Cowen cited. Read the whole paper. Looks at Covid and nursing homes. Really liked the methodology. Too many rely upon self reporting or trying to get access to financial records or reports by agencies.
I think that we had talked about this earlier and IIRC CO was really pushing for isolation among nursing home workers. While I am not opposed to trying to achieve that, I dont think most people realize how much nursing homes rely upon agencies, part time workers who work elsewhere and how much job hopping goes on. In urban areas with lots of nursing homes agencies help nursing homes keep afloat. It would take pretty drastic direct intervention to change this structure and I seriously doubt that it could be done quickly.
If you are paying people $9/hour to work in a nursing home you probably get some low skilled person worth $9/hour. You could increase that to $25/hour which would attract better trained people but there just arent a lot of better trained people lying around ready to take those jobs. That is a market based approach. You could try a govt approach and outlaw people for working at more than one nursing home but enforcement would be tough. Put people in jail if they work at more than one place? That will help a lot.
https://www.nber.org/papers/w27608.pdf
Steve
My observations are from Ontario / Quebec, Canada.
Both provinces banned workers from working in multiple homes; to address the issues of implementation — the Ontario government gave a $4 / hour raise to “frontline” workers. Both provinces also conscripted the military to supplement any home that was short-staffed. They redeployed hospital workers to nursing homes,
What bothers me is no jurisdiction in the US has even set this as goal. To try and fail is one thing; to not even try?
https://maalamalama.com/wordpress/the-public-health-disaster-of-swedens-no-lockdown-policy-/04/08/skwealthacademy